Atherosclerotic cardiovascular disease (ASCVD)

Atherosclerotic cardiovascular disease (ASCVD) is a condition characterized by the buildup of plaque—composed of cholesterol, fatty substances, calcium, and fibrin—inside the arteries. This progressive narrowing and hardening of the arteries reduce blood flow, increasing the risk of heart attacks, strokes, and other cardiovascular complications.

Major risk factors for ASCVD include high cholesterol, hypertension, diabetes, smoking, obesity, sedentary lifestyle, and genetic predisposition. Chronic inflammation and oxidative stress also contribute to plaque formation and rupture, which can lead to life-threatening events.

Prevention and management involve lifestyle modifications such as a heart-healthy diet, regular exercise, smoking cessation, and stress management. Medications, including statins, antiplatelets, and antihypertensives, help control risk factors. In advanced cases, procedures like angioplasty or bypass surgery may be required.

Early detection through regular screenings and proactive management of risk factors significantly reduce the burden of ASCVD and improve long-term cardiovascular health.

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